Selected Publications

  1. Yu-Hung Hsieh1,#, Chin-Hua Tai,1,#, Meng-Ting Yeh1,#, Yu-Chen Chen1, Po-Cheng Yang1, Chien-Ping Yen1, Hong-Jhih Shen1, Chan-Hsien Yeh2,3, Hung-Chih Kuo2,3, Der-Sheng Han4,5,* and Hsueh-Ping Catherine Chu1,*. Telomeric Repeat-Containing RNA Increases in Aged Human Cells. Nucleic Acids Research, 2025 Jul 8;53(13):gkaf597. *Corresponding author. doi: 10.1093/nar/gkaf597.
  2. Mei-Yin Liu, Keng-Ru Lin, Yuh-Ling Chien, Bing-Ze Yang, Li-Yu Tsui, Hsueh-Ping Catherine Chu, Ching-Shyi Peter Wu*. ATR phosphorylates DHX9 at serine 321 to suppress R-loop accumulation upon genotoxic stress. Nucleic Acids Research, 2024 Jan 11;52(1):204-222. doi: 10.1093/nar/gkad973.
  3. Ru-Xuan Tsai1, #, Kuo-Chen Fang1, #, Po-Cheng Yang1, #, Yu-Hung Hsieh1, I-Tien Chiang1, Yunfei Chen1, Hun-Goo Lee2, Jeannie T Lee2, Hsueh-Ping Catherine Chu1, *. TERRA regulates DNA G-quadruplex formation and ATRX recruitment to chromatin. Nucleic Acids Research, 2022 Nov 28; 50(21):12217-12234. *Corresponding author. https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac1114/6849496
  4. Chia-Yu Guh1, #, Hong-Jhih Shen1, #, Liv WeiChien Chen1,#, Pei-Chen Chiu1, #, I-Hsin Liao1, Chen-Chia Lo1, Yunfei Chen1, Yu-Hung Hsieh1, Ting-Chia Chang1, Chien-Ping Yen1, Yi-Yun Chen2, Tom Wei-Wu Chen3, Liuh-Yow Chen4, Ching-Shyi Wu5, Jean-Marc Egly6,7 and Hsueh-Ping Catherine Chu 1,*.  XPF activates break-induced telomere synthesis. Nature Communications, 2022 Oct 2;13(1):5781. *Corresponding author. https://www.nature.com/articles/s41467-022-33428-0
  5. Hyun Jung Oh, Rodrigo Aguilar, Barry Kesner , Hun-Goo Lee, Andrea J. Kriz, Hsueh-Ping Chu , and Jeannie T. Lee. Jpx RNA regulates CTCF anchor site selection and formation of chromosome loops. Cell, 2021 Nov 25; S0092-8674(21)01327-1.
  6. Hsueh-Ping Chu*, Anand Minajigi, Yunfei Chen, Robert Morris, Chia-Yu Guh, Yu-Hung Hsieh, Myriam Boukhali, Wilhelem Haas, Jeannie T Lee. iDRiP for the systematic discovery of proteins bound directly to noncoding RNA. Nature Protocols, 2021 Jun 9. *Co-corresponding author and first author.
  7. Ke-Vin Chang , Yu-Chen Chen , Wei-Ting Wu , Hong-Jhin Shen , Kuo-Chin Huang , Hsueh-Ping Chu * and Der-Sheng Han* (2020, Dec). Expression of Telomeric Repeat–Containing RNA Decreases in Sarcopenia and Increases after Exercise and Nutrition Intervention. Nutrients, 8;12(12):E3766. *Co-corresponding author.
  8. Chia-Yu Guh, Yu-Hung Hsieh , Hsueh-Ping Chu*. *Corresponding author. Functions and Properties of Nuclear lncRNAs-from Systematically Mapping the Interactomes of lncRNAs. J Biomed Sci, 27 (1), 44. 2020 Mar 17. —Review article
  9. Xiaolei Pan, Yun Chen, Beena Bijiu, Naveed Ahmed, Joyce Kong, Marti Goldenberg, Judy Huang, Nandakumar Mohan, Stephanie Klosek, Kian Parsa, Chia-Yu Guh, Robert Lu, Hilda A Pickett, Hsueh-Ping Chu*, and Dong Zhang. FANCM suppresses DNA replication stress at ALT telomeres by disrupting TERRA R-loops. Sci Rep. 2019 Dec 13;9(1):19110. *Co-corresponding author.
  10. Chen-Yu Wang, Teddy Jégu, Hsueh-Ping Chu, Hyun Jun Oh, and Jeannie T. Lee. Wang CY, Jégu T, Chu HP, Oh HJ, Lee JT. SMCHD1 Merges Chromosome Compartments and Assists Formation of Super-Structures on the Inactive X. Cell. 2018 Jul 12;174(2):406-421.
  11. Hsueh-Ping Chu, Catherine Cifuentes-Rojas, Barry Kesner, Eric Abey, Hyun Jung Oh, Myriam Boukhali, Wilhelm Hass, and Jeannie T. Lee. TERRA RNA Antagonizes ATRX and Protects Telomeres. Cell. 2017 June 29 Volume 170, p86-101.
  12. Hsueh-Ping Chu, Barry Kesner, John E. Froberg, Hyun Jung Oh, Stefan F. Pinter, and Jeannie T. Lee. PAR-TERRA directs homologous sex chromosome pairing. Nature Structural & Molecular Biology. 2017 Aug;24 (8):620-631
  13. Athanasios Zovoilis, Catherine Cifuentes-Rojas, Hsueh-Ping Chu, Alfredo J. Hernandez, and Jeannie T. Lee. Destabilization of B2 RNA by EZH2 activates the stress response. Cell. 2016 Dec 15 Volume 167, Issue 7, p1788–1802.
  14. Yi Liao, Hsueh-Ping Chu*, Zhixain Hu, Jason J. Merkin, Jianmin Chen, Zuguo Liu, Kurt Degenhardt, Eileen White and Alexey G. Ryazanov. Paradoxical roles of elongation factor-2 kinase in stem cell survival. * CO-FIRST AUTHOR. J Biol. Chem. 2016 July 27 (M116.724856)
  15. Hsueh-Ping Chu, Yi Liao, James S. Novak, Zhixian Hu, Jason J. Merkin, Yuriy Shymkiv, Bart P. Braeckman, Maxim V. Dorovkov, Alexandra Nguyen, Peter M, Clifford, Robert G. Nagele, David E. Harrison, Ronald E. Ellis, Alexey G. Ryazanov. Germline quality control: eEF2K stands guard to eliminate defective oocytes. Developmental Cell. 2014 Mar 10;28(5):561-72.